Gene-environment interactions in cardiovascular disease.

اثرات متقابل ژن- ماده مغذی در بروز سرطان؛ یک مطالعه مروری سیستماتیک

--Advances in molecular biology over the past decades have contributed to a profound understanding of the function of genes in the development of diseases. The environment and nutritional factors interact with the genetic background of subject results in development of various diseases including cancer, cardiovascular disease and degenerative nervous disorders. However, the exact mechanisms o...

The Single Nucleotide Polymorphisms in the C-reactive Protein Gene: are they Biomarkers of Cardiovascular Risk?

Recent pre-clinical and clinical studies have revealed the C-reactive protein gene (CRP) is related to the degree of acute rise in plasma C-reactive protein (CRP) levels. Moreover, single nucleotide polymorphisms (SNPs) in the CRP gene could associate with increased risk of cancer, atherosclerosis, diabetes mellitus, bowel disease, rheumatoid arthritis, psoriasis, obstructive pulmonary disease,...

A Comparison of Case-Control and Case-Only Designs to Investigate Gene-Environment Interactions Using Breast Cancer Data

Background: The traditional methods of studying the gene-environment interactions need a control group. However, the selection of an appropriate control group has been associated with problems. Therefore, new methods, such as case-only design, have been created to study such interactions. The objective of this study was to compare the case-only and case-control designs using data from patients ...

Retraction note: Association between T-786C polymorphism of endothelial nitric oxide synthase gene and level of the vessel dilation factor in patients with coronary artery disease

Gene-air pollution interaction and cardiovascular disease: a review.

Genetic susceptibility is likely to play a role in response to air pollution. Hence, gene-environment interaction studies can be a tool for exploring the mechanisms and the importance of the pathway in the association between air pollution and a cardiovascular outcome. In this article, we present a systematic review of the studies that have examined gene-environment interactions in relation to ...